Rampant use of chloroquine or hydroxychloroquine alone or with azithromycin combination caused adverse effects like diarrhea, nausea, vomiting, and QT
• Do not use chloroquine or hydroxychloroquine alone or in combination with azithromycin as prophylaxis against COVID-19 due to known harms and no
The overall results of the study showed that all patients treated with HCQ and azithromycin combination were 100% virologically cured as compared to patients (57
Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID‐19 patients with at least a six‐day follow up: A pilot observational study [published online ahead of print April 11, 2020]
2020
3%) than those receiving hydroxychloroquine
Although hydroxychloroquine has a preferred safety profile, more pharmacodynamic information is available for chloroquine
Moreover, combined therapy with azithromycin is also used after one controversial trial suggested a potential benefit [3, 4]
Ramy Mohamed Ghazy, 1 Abdallah Almaghraby, 2 Ramy Shaaban, 3 Ahmed Kamal, 4 Hatem Beshir, 5, 6 Amr Moursi, 7 Ahmed Ramadan, 8 and Sarah Hamed N
Perhaps more worryingly, compared with hydroxychloroquine plus amoxicillin, significant risks were identified for the combination of hydroxychloroquine plus azithromycin even in the short term: increased risk of angina or chest pain (calibrated HR 1·15 [95% CI 1·05–1·26]) and heart failure (1·22 [1·02–1·45]), and a doubled risk of By Dr
In this multi-hospital assessment, when controlling for COVID-19 risk factors, treatment with hydroxychloroquine alone and in combination with azithromycin was associated with reduction in COVID-19 associated mortality
Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed‐dose azithromycin and chloroquine combination tablets
Corticosteroids and tocilizumab were given to a various number of patients in both
Billions of doses of chloroquine have been administered worldwide over the past 70 years but conc