N Untreated Pneumocystis pneumonia is associated with a mortality of 90% to 100%
While there is no recommendation for high dose influenza vaccination, a randomized trial of high vs standard dose in HIV-infected adults showed increased seroprotection rates against H1N1 (96 vs 87%) and influenza B (91 vs 80%), but not H3N2 (96 vs 92%)
Simple Antibiotic Switch for Pneumonia Patients Could Prevent Hospital Infection
Unnecessary use or misuse of any antibiotic can lead to its Zithromax or Z-PAK (azithromycin) is a semi-synthetic macrolide antibiotic used for treating: otitis media (middle ear infection), tonsillitis, laryngitis, bronchitis, pneumonia, and sinusitis caused by susceptible bacteria
Treatment for bacterial pneumonia is the same for patients with HIV infection as for the general population
Azithromycin belongs to the class of drugs known as macrolide antibiotics
Azithromycin belongs to the class of drugs known as macrolide antibiotics
Azithromycin is reserved for patients with substantial intolerance to clarithromycin or when drug interactions with clarithromycin are a concern (strong, low)
avium was the etiologic agent in >95% of people living with HIV with advanced immunosuppression who acquired disseminated MAC disease
Or 500mg on day 1 followed by 250mg on days 2 to 5
Opportunistic infections (OI) are a significant cause of morbidity and mortality in patients with HIV/AIDS
PO (Children ≥ 6 mo): Pneumonia/Pertussis: 10 mg/kg (not to exceed 500 mg/dose) on 1st day, then 5 mg/kg once daily (not to exceed 250 mg/dose) for 4 more days
When comparing the 2 therapies, patients treated with azithromycin had a mean LOS (±SD) of 7
Bottom Line
May be taken with or without food; however, azithromycin may be better tolerated if taken with food
Usual Adult