Our aim
09220
Core Study
4-fold increases in area under the plasma concentration-time curve and 1
Improvement of graft-versus-host disease prophylaxis remains an important goal in allogeneic hematopoietic stem cell transplantation
Since both drugs share similar transport and metabolic pathways, there is the potential for an interaction leading to
SRL
Sirolimus (Siro), an inhibitor of the mammalian target of rapamycin (mTOR)
Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study Nephrol Dial Transplant
We hypothesized that the Pgp activity level may affect cyclosporine cytotoxicity
Cyclosporine is an immune suppressive drug used in the treatment of immune diseases and transplant rejection
Cyclosporine has not been associated with instances of acute liver failure or vanishing bile duct syndrome
Case report: This report describes a unique case of rabdomyolysis secondary in which ciprofibrate
This study was conducted to evaluate the pharmacokinetics (pk) and drug interactions between cyclosporine (CsA) and sirolimus (SRL) in kidney transplant recipients
) pk of CsA (4-5 mg/kg/dose) and SRL (2 mg, n = 20; 5 mg, n = 33) were evaluated on day 7 (n = 53)
1% repeat renal transplant recipients, and 13