Plaquenil (hydroxychloroquine) is a prescription drug used for certain types of arthritis, lupus, and malaria
Some people have a serious side effect from hydroxychloroquine
Hydroxychloroquine was stopped and she was admitted in ICU for septic shock
There are 85,611 people reported to have side effects when taking Plaquenil
Febrile neutropenia is a serious risk in severely neutropenic individuals with either solid or hematologic malignancies
These people tend to be female, 50-59 old, have been taking the drug for < 1 month
The phase IV clinical study analyzes which people take Plaquenil and have Agranulocytosis
Leucopenia and thrombocytopenia may complicate treatment with azathioprine, methotrexate and rarely, cyclosporine mycophenolatemofetil or hydroxychloroquine
Adverse hematologic effects including neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia have been rarely associated with 4-aminoquinolines
The most common (up to 50%) side effects of hydroxychloroquine are gastrointestinal events such as vomiting, diarrhoea, nausea
Zeh et al
Felty’s syndrome (FS) is a rare disease defined by the presence of 3 conditions: rheumatoid arthritis (RA), neutropenia, and splenomegaly 1
Hydroxychloroquine has attracted attention in the treatment of COVID-19
Hydroxychloroquine (HCQ) has in vitro activity against SARS-CoV-2 and is an FDA-approved medication for malaria and rheumatologic disorders [6, 7]
knowlesi, P
lower back or side pain
Hydroxychloroquine (HCQ), one of the oldest drugs used in rheumatology, came recently into attention as one of the potential therapies tested for the severe acute respiratory syndrome coronavirus-2 disease treatment
Figure 1