86, Zofran) occurs as a white to off-white powder that is sparingly soluble in water and in alcohol
Jul 4, 2023 · When taking the oral soluble strip film, use dry hands to remove the strip and place it on your tongue
Water is used as a medium for complexation because the drug is soluble in water
Water Solubility: 0
Ondansetron is a weak base (pKa = 7
Ondansetron HCl is a white to off-white powder that is soluble in water and normal saline
14) Parent Compound CID 4595 (Ondansetron) Component Compounds CID 4595 (Ondansetron) CID 962 (Water) CID 313 (Hydrochloric Acid)
Once the film is dissolved, you
V
5%, and DL of 10
When taking the oral soluble strip film, use dry hands to remove the strip and place it on your tongue
Uses Warnings Before taking Side effects Dosage Interactions FAQ What is ondansetron? Ondansetron blocks the actions of chemicals
Dry the precipitate in an air oven for 1 h Apparatus 2: 50 rpm at 105°
Ondansetron is a weak base (pKa = 7
The solubility is markedly reduced in solutions for which the pH greater than or equal to 6
Special care may be needed
Ondansetron tablets, USP for oral administration contain ondansetron hydrochloride USP (dihydrate) equivalent to 4 mg or 8 mg or 24 mg of Ondansetron hydrochloride was appropriately weighed and transferred to 100 ml volumetric flask containing 50 ml of methanol
Ondansetron hydrochloride is the soluble form of ondansetron, The mobile phase was composed of methanol with water and diethylamine as additives (MeOH/H 2 O/DEA – 98/2/0
3 ± 0
Ondansetron tablets, USP for oral administration contain ondansetron hydrochloride USP (dihydrate) equivalent to 4 mg or 8 mg or 24 The tested saturation solubility of ondansetron hydrochloride dihydrate in water is 28
It is also used to prevent nausea and vomiting that may occur after surgery
Bio Activity: Ondansetron HCl dihydrate is a white to off-white powder that is soluble in water and normal saline
It gives reaction (a) of chlorides (2
36 is the molecular weight of ondansetron; 100 is the conversion factor to percentage; L is the Apparatus 2:50 rpm
Oral and intravenous dosage forms of OND are commercially available
, 5 mg and 10 mg strength tablets, for the treatment of emesis
The empirical formula is C 18 H 19 N 3 O•HCl•2H 2 O, representing a molecular weight of 365
Each 4 mg ondansetron tablet, USP for oral administration contains ondansetron hydrochloride, USP equivalent to 4 mg of ondansetron
25 mg of sodium citrate dihydrate, USP as buffers in that is sparingly soluble in water and alcohol
2, 4