Updated 09/30/2022
Dutasteride and finasteride are two popular 5alpha-reductase inhibitors
The effect of short-term use of finasteride versus cyproterone acetate on
WASHINGTON – Congress has agreed on a short-term
Finasteride administered 30 days before surgery appears to decrease the apoptotic factors caspase-7 and IGFBP-3 in cancer cells, while having little to no effect on caspase-3, insulin growth factor-1, bcl-2, p53 and p21
However, an apparent increase in high-grade disease was also observed among men
Other long-term clinical studies of finasteride demonstrate similar results, with a 1-milligram dose being generally well tolerated
Finasteride is an effective treatment for hair loss in men at 1 mg per day
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Comparing short to long‐term therapy, finasteride does not improve symptoms significantly better than placebo at the short term, but in the long term it does, although the magnitude of differences was very small (from < 1
Proscar Long-Term Efficacy and Safety Study Urology
Purpose: We reviewed the available data on the effect of finasteride on serum levels of prostate specific antigen (PSA), PSA velocity and PSA density in men with benign prostatic hyperplasia (BPH) and prostate cancer
Finasteride blocks the conversion from testosterone to dihydrotestosterone (DHT) by inhibiting 5α-Reductase type II and III
Finasteride is shown to be reasonably tolerated in both men and women; however, patients need to be educated about the possible short- and long-term side-effects
81 [95% confidence interval (CI), 1
Ozden C, Benli K, Gokkaya S, Bulut S, Memis A