Rivaroxaban and amiodarone

The combination of rivaroxaban and amiodarone increased the risk of bleeding in patients with atrial fibrillation, especially clinically relevant nonmajor and minor bleeding. When the 2 drugs were co-administered to young, healthy subjects, exposure Jul 11, 2017 · For example, amiodarone has been associated with increased odds of bleeding in patients taking rivaroxaban, 16 and patients who had major bleeds on rivaroxaban appeared twice as likely to be taking a P-gp inhibitor with or without a CYP3A inhibitor

2024-03-29
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  1. 1a), and the effects were more pronounced in elderly patients
  2. 5=Flecainide
  3. Anagrelide
  4. 044
  5. valvular heart disease
  6. 5% were females, 41
  7. Other drugs that have the same active ingredients (e
  8. ; ROCKET AF Investigators
  9. nausea, vomiting, diarrhea
  10. g
  11. 2018; 71 (12):1395-1397
  12. Beta blockers should be tapered and discontinued
  13. mm
  14. renal disease
  15. Interactions
  16. 1
  17. g
  18. Amiodarone Fluvastatin (Lescol) Gemfibrozil (Lopid) Garg J, et al
  19. 7%; apixaban, 14